|
|
|
|
김현희 ( Kim Hyun-Hee ) - 부산대학교병원 간호부
김정순 ( Kim Jung-Soon ) - 부산대학교 간호대학
|
|
Abstract
|
|
|
|
|
Purpose: To assess the efficacy of subglottic secretion drainage in preventing ventilator associated pneumonia.
Methods: We included randomized clinical trials of mechanically ventilated patients that had compared with standard endotracheal tube care and subglottic secretion drainage. We identified eight randomized clinical trials that met the inclusion criteria with a total of 2112 randomized patients. Studies were meta-analyzed by Review Manager 5.1.
Results: The overall risk ratio for ventilator-associated pneumonia of subglottic secretion drainage was 0.55 (95% CI: 0.44~0.70; p<.001) with no heterogeneity (p=.41; I²=2%). There was no effect on hospital (RR=0.93; 95% CI: 0.76~1.13; p=.45) or intensive care unit (RR=1.04; 95% CI: 0.86~1.24; p=.71) mortality. Both intermittent subglottic secretion drainage (RR=0.47; 95% CI: 0.34~0.64; p<.001) and continuous subglottic secretion drainage (RR=0.69; 95% CI: 0.49~0.97; p=.03) was effective in the reduction of ventilator associated pneumonia.
Conclusion: Subglottic secretion drainage is effective for the prevention of ventilator-associated pneumonia. However clinicians must take effectiveness and safety into consideration at the same time, applying subglottic secretion drainage.
|
|
|
KeyWords
|
|
성문하 분비물 배액, 인공호흡기, 폐렴, 예방, 메타분석
Subglottic secretion drainage, Ventilator-associated pneumonia, Prevention, Meta-analysis
|
|
|
원문 및 링크아웃 정보
|
|
|
|
|
등재저널 정보
|
|
|
|
|
|
|